What medicines can treat PMS symptoms?

Over-the-counter and prescription medicines can help treat some PMS symptoms.
Over-the-counter pain relievers you can buy in most stores may help lessen physical symptoms, such as cramps, headaches, backaches, and breast tenderness. These include:
Ibuprofen
Naproxen
Aspirin
Some women find that taking an over-the-counter pain reliever right before their period starts lessens the amount of pain and bleeding they have during their period.
Prescription medicines may help if over-the-counter pain medicines don’t work:
Hormonal birth control may help with the physical symptoms of PMS, but it may make other symptoms worse. You may need to try several different types of birth control before you find one that helps your symptoms.
Antidepressants can help relieve emotional symptoms of PMS for some women when other medicines don’t help. Selective serotonin reuptake inhibitors, or SSRIs, are the most common type of antidepressant used to treat PMS.
Diuretics (“water pills”) may reduce symptoms of bloating and breast tenderness.
Anti-anxiety medicine may help reduce feelings of anxiousness.
All medicines have risks. Talk to your doctor or nurse about the benefits and risks.